April 20th, 2017, 1941 hours, tonight, our first cargo shipSkyboat oneIt will be launched into space from the long march 7 rocket, which will meet with sky palace ii space laboratory in orbit for six months. One of these is a life science project from zhejiang: the team laboratory of professor wang kim fook, zhejiang university school of life sciences, which will carry sky boat i into space with the human marrow-filled stem cells to conduct a bone cell orientation separability experiment。
Together, we are about to witness how a group of "made in zhejiang" cells have washed out of earth and grown in space
Wong kim fu is at the launch base
Why send stem cells to heaven
Scientists want to figure out what's unusual about stem cells in bone marrow in microgravity。
The initial motivation for exploring such “unusuals” was that since the first human race out of the earth in 1961, all astronauts had returned to earth for some time with “soft legs” and no walking or standing up. Good guys have to be soft just because of a change in gravity? It must be life-support cells that have changed。
Previous studies by scientists have shown that astronomers have increased bone loss in microgravity environments。
Previously, on 6 april 2016, the stem cells of the wang kimford laboratory had been lifted from the scientific experimental satellite “practice x” with china's first microgravity science experiment. The wang jinford team's experiments have shown that in space microgravity conditions, not only do humans lose calcium, but even the mechanisms for creating calcium. The amount of stem cells transformed into bone cells is much less than the amount produced by experiments on earth。
The wong kimfort team was the first team in the world to prove this conclusion through an actual microgravity experiment in space。
What's the difference with this lift
An analysis of the results of the experiment in practice 10 shows that in microgravity environments, both bone loss and generation work together, resulting in severe osteoporosis among astronauts. However, the process of directional separation of stem cells into bone cells has not been followed in a detailed and visual way in a truly space microgravity environment。
So stem cells are going up again。
After docking with sky miya ii, the reactor will begin work. Every movement of cells in space is observed in real time by scientists on earth。
It was described that human cells were connected to each other to form a network structure by connecting each other with the extraterrestrial matrix. Integration is a protein that connects to the inside of the cell and a substance that connects to the extra-cell matrix。
Microgram of cell skeleton
On earth, the extracellular matrix of cells is subject to force and patterns change. They transmit aggregate messages to the integrator, bringing together the proteins connected to the integrator to form a stickle。
These spots are important in order to activate the activity of the enzyme in the cell and induce protein activation in the cell to promote bone cell formation。
The earth's formation of viscous micrograms is large and numerous
The wang jinford laboratory speculates that the ability to generate bone cells is reduced by the practice of stem cells on number 10 because, in weightlessness, adhesive spots may not be properly formed. “this led to the failure of the entire subsequent signal route.”
Wang wants to see this process for himself when skyboat one's on track。
Is this research only about astronauts
This matter is relevant to every human being in the sky: astronauts are unable to produce calcium normally because of their weightlessness; and people on earth, as they age, will have the same problem。
Understanding this mechanism will help humans to develop molecular drugs that work on bone cell generation。
In cases where calcium is neither properly produced nor constantly lost, it is not enough to exercise alone。
Even if you don't want to go to space in your life, you'll probably feel the dilemma of being soft on earth。
According to statistics, there are 8. 9 million fractures per year globally, and we now have about 90 million osteoporosis patients。
"we've managed it with small molecules in the lab, and we've found that it actually enhances the generation of bone cells in a weightless environment." wang kim fu said。
However, an experiment by the wong kim fu team found that the reduced ability of stem cells to divide bone cells was accompanied by a greater power to divide into fat。
This experiment will explore, for the first time in the world, the causes of the impact of the microgravity environment in space on the potential for stem cell separation。
