High-throughput automatically diluted the tolerance value
The high-throughput automatic dilution capacitors, through integration automation, high-precision control and modular design, have significantly improved the efficiency, accuracy and safety of laboratory liquid processing, the value of which is reflected in the following core dimensions:
I. Efficiency revolution: from “hour” to “minute” viet
Batch capacity enhancement
Multi-channel parallel processing: mainstream equipment supports 8-32-channel synchronization, for example, when standard curves are prepared, five gradient concentrations (e. G. 1 μg/ml, 5 μg/ml, 10 μg/ml, 20 μg/ml, 50 μg/ml) can be completed in one-time dilution, taking only 5-10 minutes for individual batch processing, while manual processing takes approximately 1-2 hours。
High-throughput micro-pore support: for example, mdpro 400 high-throughput gradient diluters can process 1-4 micro-pores at the same time, completing 320 plates (approximately 30,000 concentration ratios) in eight hours, increasing the speed of research and development of drug antibodies by more than 10 times and expanding the screening range by 10 times。
Fluid linework
Sampling, cleaning and fitting links are seamlessly integrated into a closed loop process of “mechanical hand trans-shipment-jet-smoke-ai visual prosthesis-active discharge” to reduce equipment idle time. For example, in microwave digestion or electrothermal digestion scenes, 30 samples could be processed in single batches, 75 per cent shorter experimental cycles than traditional methods。
Accuracy leaps: from “experience dependency” to “measureability control”
Double security between trace and mass
High-precision injection pump: μl-scale micro-calculation (with a better accuracy than ±0. 05 ml) by means of a step-up electric power drive, e. G. By diluting the standard solubility at a concentration of 1 ml of 1,000 mg/ml to 10 mg/ml for work fluids, the volume error can be controlled within ±0. 01 ml。
Large flow continuous infusion pump: achieve l-level bulk adhesion (velocity 2 ml/s), taking into account efficiency and accuracy。
Ai visual palsy technology
Accelerator industrial cameras (e. G., 2472 x 2062 pixels, 49. 0fps), combined with ai algorithms, capture liquid surface dynamics in real time and raise the degree of conceivance to less than 0. 5 mm through image processing techniques to meet national standards for b-volume bottles. For example, in drug research and development, the technology ensures that the concentration of the active ingredient is less than 0. 1 per cent and avoids the end-of-life of batches due to matching errors。
Dynamic mixed optimization
Diluent fluids are rapidly mixed with parent fluids in the mixed cavity by streaming or static mixers (e. G. Ptfe blades), which can be controlled within 0. 1-1 seconds. System changes in feedback concentration through uv-visible spectrometer, dynamic adjusted flow ratio, final concentration fluctuations
Safety enhancements: from “manual exposure” to “closure protection”
Corrosion and pollution prevention design
For strong acid, strong alkalin, organic solvents or toxic samples (e. G. Cyanide, heavy metal parent fluids), equipment uses corrosive resistant materials (e. G. Polytetrafluoroethylene pipelines, quartz glass containers) and sealed operating modules to avoid reagent contact with humans, while preventing reagents from volatile contamination of the environment。
Cross-pollution between samples is completely eliminated by a single-use head or automatic cleaning function, such as in food safety tests, which can handle both vegetable samples containing pesticide residues and high-fat dairy products and ensure the independence of detection data。
Reduced occupational exposure
The whole process is completed in a closed cavity, and the tester is not exposed to highly corrosive or hazardous reagents to avoid occupational exposures such as burns and poisoning. For example, in the field water quality, heavy metal contamination emergency detection, systems can rapidly build mobile laboratories on site to reduce direct human contact with pollutants。
Application scenario expansion: full coverage from laboratory to production lines
Biomedicine
Cell therapy: automation of the car-t cell culture base to increase cell expansion efficiency by 30 per cent through precise control of cell factors such as il-2。
Vaccine production: ensure that the mix of antigens and appurtenants is less than 0. 5 per cent error and ensure consistency between batches。
Drug screening: support for high-throughput screening (hts) with a single-day leap from 200 to 4,000 compounds, significantly reducing the research and development cycle。
Environmental monitoring
Heavy metal detection: gradient dilution from 1 ppm to 1,000 ppm can be automatically completed and pre-treatment needs for complex samples such as soil, water bodies, etc. Can be adapted。
Emergency testing: rapid deployment of mobile laboratories in the field to dilute the gradients of elements such as lead, cadmium, mercury and icp-ms by pre-positioning the database, reducing the time between sampling and reporting from 24 hours to 4 hours。
Food safety
Testing of pesticide residues: automatic completion of pre-treatment steps such as sample acidification, solid phase extraction, dilution tolerance, reduction of the test limit from 0. 1 ppm to 0. 01 ppm to meet the latest eu standards。
Additive detection: full chain data from farm to table are traced to the lims system。
Cost optimization: from “high and inefficient” to “favourable management”
Reduced human costs
Through automated processes and parallel processing, the duration of single batches has been reduced from four hours in traditional methods to two hours, reducing human costs by more than 60 per cent. For example, in the food sampling scenes, new recruits require only one or two hours of equipment operation training, which will allow them to complete the dilution process independently and significantly reduce the cost of training laboratory personnel。
Reduction in reagent waste
Precision and capacitation reduce reagent waste, ai visual systems avoid duplication of operations and combined costs decrease by 30 per cent compared to traditional methods. For example, in soil heavy metal tests, 10 samples took a total of 18 minutes, were five times more efficient than manual and met the standard of jjg196-2006, level b。
Future trends: deep integration of intellectualization and modularization
Smart algorithm optimization
Forecast dilution pathways through in-depth learning models to reduce reagent consumption and operating time. For example, the system can automatically adjust the diluting gradient to the initial concentration to avoid overdilution or insufficient concentration。
Modular extension
Support the seamless interface with equipment such as auto-introductors, mass spectrometers and the construction of a fully automated platform for "sampling in-out". For example, when detection instruments find sample concentrations beyond linear ranges, automatic feedback signals can be sent to diluting condensing devices to initiate secondary dilution without manual intervention。
Cloud platform integration
Experimental data are uploaded to clouds in real time, allowing remote monitoring, sharing of methods and multicentre collaboration. For example, laboratories can ensure data consistency at global branches by sharing standard curve-formulation methods at cloud level。
Related labels: fully automated high-throughput sample dilution condensing system fully automatic dilution frame laboratory capacitors
