This newspaper (journalist zhuhanbin), led by a team of researchers from guangzhou institute of biomedicine and health, has revealed the scientific principles of chemical methods for the preparation of stem cells and developed simple, efficient and standardized methods for the preparation of stem cells, providing new perspectives and programmes to induce research and optimize the preparation of multi-energy stem cells. The results were published online on april 6, in the magazine cell-link。
It is understood that induction of multi-energy stem cells can help humans understand the mystery of cell “conversion” and provide a window for the scientific community to spy on the nature of life. Multi-energy stem cells can also be used for the regeneration of new tissues and organs, providing “seed” cell sources for disease treatment and regenerative medicine. Japanese scientist shinaka yamayama, winner of the 2012 nobel prize for physiology or medicine, used viral carriers for genetic transport. However, this has a potential carcinogenic potential and is at greater risk for subsequent clinical applications. Scientists in various countries have been developing new methods to induce body cells to become multi-energy stem cells. At a later stage, scientists used chemical micro-molecular substitutes to induce polyenergy stem cells from the mountains, but there were shortcomings such as multiple steps, long periods of time, inefficiency and lack of clarity。
The pei teng has developed an efficient, simple chemical small molecule to induce multi-energy stem cells. Its acronym is cip, which is the multifunctionality of compounds induced stem cells. The programme requires only two different “waters” for cells to “baptize” in order to “return to childhood” to stem cell status. This method is simpler and more efficient than previous programmes and requires fewer initial cells. More importantly, a variety of body cell types can be achieved “return to childhood”, including hepatic cells that are extremely difficult to cultivate in vitro。
“the study has placed our country in the world's leading position in the field of compound induction of polyenergy stem cells.” xiehin, researcher at the shanghai institute of medicine and deputy director of the national centre for the screening of new medicines at the central college of sciences, said that the methodology could guide scientists in the targeted design of small molecules of compounds to change dye structure, thus further optimizing the chemical induction reprogramming system。
