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  • Technology weekly, fluorescent detection: from false labels to tumor tumours, aie materials transfor

       2026-04-21 NetworkingName1590
    Key Point:Aie's "family" opens upIt's getting widerOver the past 20 years, more than 2,200 scientific institutions from 76 countries and regions have conducted research on this new material, which has also enriched the aie material system and provided a wider range of applications. Today, the aie material family has developed family members such as hps (hexaphenyl enzyme), tpe (tetrastyrene), tpp (tetraphenyl enzyme), dsa (distyrene distyrene diethylene) w

    Aie's "family" opens up

    It's getting wider

    Over the past 20 years, more than 2,200 scientific institutions from 76 countries and regions have conducted research on this new material, which has also enriched the aie material system and provided a wider range of applications. Today, the aie material “family” has developed “family members” such as hps (hexaphenyl enzyme), tpe (tetrastyrene), tpp (tetraphenyl enzyme), dsa (distyrene distyrene diethylene) which, in addition to producing different wavelengths, have various characteristics: some are well membrane, suitable for large areas of old and chemical sensor film production; others are suitable for near-infrared imaging and photothermal treatment; others are widely used for “naked eye” chemical sensors

    Fluorescent probe recognition machine

    This is the first time that iae materials have become more widely used

    Thanks to the original discovery of aie materials, tang benzhong was awarded the first prize for natural sciences 2017. Aie materials have also begun to shift from scientific findings to outcomes. In 2020, aie was rated by the international union of pure and applied chemistry (iupac) as the top 10 emerging technologies in the field of chemistry。

    Tang ben used his cell phone as an example: "our cell phone display screens use old organic light diodes, but when existing materials are made into thin film, the ability to aggregate light is reduced. The use of aie materials for oled is not the same, and this material is becoming more concentrated, and therefore oled is one of the most promising applications of aie material.”

    In 2024, tang benzhong served as a strategic science and technology adviser to the tokyo oriental corporation as the lead director of research in the field of organic photovoltaics, particularly in the collection of aluminum (aie). He will provide strategic advice and technical guidance to the east of the country in the areas of new displays, optical appliances, etc。

    The results were translated into guangzhou:

    Virus detection, tumor detection, forgery prevention..

    Don benzhong and guangzhou have an unsolvable relationship. He was a “three-year-old” graduate of the south china polytechnic university in 1978, who was able to study abroad and return to teach in hong kong, maintained a deep friendship with guangzhou, and had excellent cooperation in the study of maternity studies at the primary school. In 2015, tang benzhong was named “honorant citizen of guangzhou city”. In may 2020, the china university of technology, located in guangdong province, was established in the hoang poi district. Tang benzhong is the director of the institute and has helped to transform the aie front-line material in guangzhou。

    Wang zhi minh stated that in the five years since its establishment, the aie institute has been committed to autonomous research and development of innovative technologies and has won over 50 national invention patents. The aie material, a new and cutting-edge material, is still in the market development and expansion stage. The institute has now established a joint laboratory and application demonstration base in cooperation with hundreds of hospitals, enterprises and scientific research institutions throughout the country, including the general hospital of the southern field of the people's liberation army and the guangzhou medical examination centre ltd。

    Wang zhi minh, senior vice-president of the aie institute and researcher at china polytechnic university, told journalists that, at present, aie has developed a variety of products using aie materials, which can be divided into functional microballs, functional materials, public safety, scientific materials and in vitro diagnostics。

    Fluorescent probe recognition machine

    The aie material system is becoming richer。

    Functional microball application

    A well-known test reagent box, using a technique known as glue gold, is not sufficiently sensitive to detect markings at a certain level. The team introduced aie fluorescent microball technology into the reagent box, which is equipped with a functional foundation to enable it to connect efficiently to target protein dolls, especially for hyper-sensitized fluorescent immunodeficiency analyses. “we have developed a number of test kits based on aie fluorescent microball technology, which detect viruses such as kikunkenja, zakat, dengue fever, and various drugs. The advantage of aie's fluorescent detection reagent box is that it takes only a few minutes to complete the test. It is resistant to interference and can be tested quantitatively, and the sensitivity of testing is 2-3 orders of magnitude higher than that of glue gold.”

    Application of scientific materials

    The team developed multiple aie fluorescent probes. Cellular imaging fluorescent probes with a concentrated induction (aie) effect are capable of maintaining weak fluorescent signals in the solution and cell environment. Once entered and integrated with the target structure, their fluorescent signals are significantly enhanced and are widely used in disease studies, drug screening and related experiments. For example, in cancer therapy, when aie fluorescent probes are injected into the body, tumor cells can be “lighted”, leading doctors or operating robots to more complete tumour surgery. Aie materials can also be used in the precise location of the embolism in haemoemic treatment。

    Functional material applications

    The institute has developed products such as aie fluorescent anti-forger oil ink, aie fluorescent fibres, lithium cell membrane polymer microcoding, optical resin, precious metal enrichment. Wang zhi minh explained that in the area of fraud-proof ink, the institute was working with a liquor company in qingdao on the development of anti-false markings, and that aie fluorescent anti-false ink had been made from resins and aie molecules through special processes. In sunlight, the print is colourless or light, and the fluorescent colour is strong at 365 nm ultraviolet light and can be used for various commodities. Aie fluorescent fibres display white or colour in natural light, can produce strong fluorescent colours after being activated by uv light of 365 nm, have the advantage of high fluorescent brightness, good water-resistant washing, application of wide fibre materials, etc., and can be applied to forgery protection in the areas of fabric clothing, securities instruments, etc。

    Fluorescent probe recognition machine

    Aie fluorescent fibres are white or coloured in natural light and can produce strong fluorescent colours when uv light is activated at 365 nm。

    Public safety applications

    Aie material is also very relevant for forensic purposes. The team developed the aie magnetic fingerprint powder, which is suitable for showing fingerprints on all non-permeable objects and some semi-permeable objects, as an alternative to market fluorescent. Photomagnetic powder, high fluorescent brightness, high resolution, free of background interference, non-destruct of dna, non-toxic. The team developed an aie fingerprinting suspension solution, which can be used for fingerprinting in a damp or immersion environment, as well as for non-permeable and partially permeable objects, with the same advantages of low background interference, high brightness and strong adsorption. At the crime scene, many hidden blood traces may be key to solving the case, and the team developed an aie submersible reagent, which applies to the presence of fresh or older, diluted or unreduced blood traces, which can be coloured in small quantities, showing important advantages, such as persistent colour and non-destructing dna。

    In addition, aie can detect drugs and explosives. More than a dozen common drugs, such as morphine, meth, ecstasy, pheasy, fentanyl, trinitromethamphetamine (tnt), dinitromethamphetamine (dnt), black powder (bp), nitrobenzene (nb), nitromethamphetamine (mnt), bitter acid (picricacid), heckin (rdx) and tetrayl, are currently being tested at the institute。

    Food safety applications

    Food security is an important part of public security. The institute has developed products such as an introduction and hand-held food safety quantitative fluorescent detector and a pre-safety food treatment unit, which allow high sensitivity detection of pesticide residues, fungal toxins, veterinary residue and illegal additions in food。

    Scientists talk about innovation

    Don benzhong, academy of sciences, china: critical thinking in scientific research

    From the laboratory's "scrambling light", to the aie material's "all over the world", donmoto's loyalty is very touching。

    He told journalists that science has evolved to this day with many mature theories, models, frameworks, and that the best things are almost all written in textbooks. They all seem to have gone through a thousand and many questions. But many science is always relative, not absolute。

    Tommoto said, for example: “before quantum mechanics, newton mechanics was in the classic physical world almost `smuggling the world', but not when newton mechanics came to the `microworld'. If you thought newton mechanics would never be wrong, you wouldn't have any innovation." tang benzhong stated that scientific research must be conducted with critical thinking and not blindly disproved to achieve unique achievements。

    Fluorescent probe recognition machine

     
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