Imagine's been watching the growth of the red bean sprouts
In recent days, a group of viol from fujian southern pharmaceuticals inc. Has flown to hunan, sichuan, etc., where it will become a formulation for sale throughout the country and even around the world。
Vishuol is a natural anti-cancer drug derived from a growing red beanwood, which, owing to its low volume and high cost, was worth up to $2 million. Mingbrook county is one of the more productive areas in the southern red bean sprouts, where the method of artificial breeding of red bean sprouts was born, and the technology of extraction of chrysanol was introduced, with a step-by-step bid for a departure。
From the town of minghu county, after a half-hour stretch, journalists came to the dense forest of the port village of shahu. And as they climb down narrow mountain paths, many of the red bean sprouts come into the curtains, and branches are connected and leaves are folded. Here, it's a “secret base” for residual energy。
Yuen jian is the director of the mingbrook red soywood industrial research institute. More than 20 years ago, he buried his first seed here。
It's a piece of dirt. Topic
The 85-year-old is fit and goes up the mountain twice a week. Checking, cutting, recording, and the rest of it can be done with more strength. This year, it's his 28th year of dealing with red beanwood。
Red beanwood is also known as purplewood. Red bean sprout is a treasure, with a combination of combinations of meds, high-quality wood, greening, basin view, so many late-stage cancers, such as breast cancer, are particularly effective when extracted from the bark and leaves。
Southern red bean sprouts became endangered plants in 1994. It is legally protected against logging。
Mingbrook of the mountain water show is one of the more productive areas of the wild southern red beanwood. At the same time, wild red bean sprouts are heavily dependent on birds feeding their seeds and excrement is highly unstable. The artificial seedlings of red bean sprouts once became a worldwide problem。
At that time, the ministry of forestry received the first prize for scientific and technological progress for breaking through the fast-growing ponytail pine application. Intoxicated by scientific research, he decided to challenge the artificial seeding of red beanwood。
Into the courtyard, the flower pots, of all sizes and sizes, are covered in every corner. “i see my home as a laboratory, and each basin is covered with a variety of material.” in the first few years, after a few years, he's been thinking about how to attack red beanwood. “the seed embryos are wearing three layers of hard `overcoats', such as waxes, wooden embolisms, stone cells, etc., resulting in the prolonged hibernation of the embryos with water and oxygen deficiency.”
After a long period of hard observation and waiting, he gradually found the “sand-cover” method — burying the seeds in wet sand soil, decomposing the skin of the seeds and restoring them. Finally, after two winters and a summer, the seed of the experiment broke through the sand and grew green。
Overcoming one of the most difficult growth barriers, the residual capacity continues to break through the technical challenges of integrated breeding techniques such as fertilization, shade and pest control. In 1996, in mingbrook, for the first time, i succeeded in artificially nurturing 25,000 seedlings of southern red bean sprouts。
At that time, the world was in great demand for vermouth alcohol, but actual production was less than one tenth of the demand. Mingbrook is aware of its value and has been able to develop the mangrove industry throughout the county. Soon the county distributed seedlings to farmers. In 2001, the first chinese training course on red beanwood cultivation was held at mingbrook. "at that time, i spent $5,600 a month on the telephone, all of them farmers consulting on planting techniques."
More than 50,000 acres of red bean-wood have allowed many local farmers to grow wealth and brought mingbrook into the eyes of the pharmacists。
Rooting - innovative extortion technology
The car's red bean sprout leaf was sent to no. 29, red bean sprout ii, mingbrook county, where fujian southern pharmaceuticals co. Ltd. Is located。
Looking back at the company's history at sagan ming creek, the key word for general manager li yong was “hard”。
In 2001, mingxiu county introduced the university of redwood viol extraction technology and established the southern biology company ltd., but in the following years the company has not been very optimistic. In 2007, the company was renamed fujian southern pharmaceuticals corporation, inc., and li yong-il was ordered to lead the company to gain or lose。
On the other hand, vervainol was dubbed “plant gold”. “on the international market, the price of 1 kg of verviol can reach $2 million, while technology for the development of raw materials for violol has been monopolized abroad. “the huge market potential has enabled li to accelerate the process of industrialization of chrysanol。
In 2009, r & d technologists from the great lakes sea gathered in the south, among them the luang ping。
Into the production workshop, red beanwood raw materials are passing through ultrasound extraction equipment, with a constant flow of separation and purification to the other side. "in addition to obtaining a very small amount of natural vigorol, another substance, 10-dab, which is distilled in liquids, can generate semi-synthetic vigilol by multi-step chemical reactions, resulting in a significant increase in its production."
However, that outcome was not easy. Since 2008, the southern pharmaceuticals, in cooperation with the university scientific team, have gradually mastered the “semi-synthetic vigil” process, but, according to pitt, “through artificial impregnation and boiling, a ton of raw materials can produce only a few kilograms of vigil, which is inefficient and energy-intensive”。
The high-temperature laboratory, which stimulated the mixture of gas and sweat, was once the "nightmare" of the beam. “the raw materials and the boiled steam of methanol come out of the line of reaction, even with the `hog nose' mask, and they can't open their eyes. “the poor conditions make manual extraction unsustainable。
It must be broken! In 2011, the technical team tried ultrasound. Team acquisition of ultrasound instruments, ranging from minor to mid-test and continuous adjustment of process parameters made critical progress in 2013. “susonic extraction has increased efficiency dozens of times!” the saber-pill says, “it's like tea, which used to be 10 times a day, and it's now time to take all the material out of the tea once in an hour, without human effort.”
With the "foot product" viol, southern pharmaceuticals became the first “new board 3” listed enterprise in saming city in 2014。
Growth - cost reduction for preferred varieties
At the same time, a difficult issue lies ahead。
Owing to the low levels of soybean sushi alcohol in the southern part of the country, the company also spends tens of millions of yuan annually to import high levels of red bean sushi raw materials from europe. While optimising the process, li yong had to take the team to find a better herring。
“at most, hundreds of samples will be measured in one day, comparing over and over again the selected species with the highest concentration.” the head of the ministry of plantation zhou gui bin recalled that, over the past two years, south one had emerged from tens of thousands of experiments and had a ovine content more than 50 times higher than the original species. Today, 3,000 acres of south one cover five townships in mingbrook, saving more than 70 per cent annually。
As a core component of the drug, raw materials are considered to be “chips” in the pharmaceutical industry, which is crucial in the chain of “complex chemicals - intermediate - feedstocks - cdmos (contract-orientated r & d production services) - finished drugs.” “in the country, the production of raw pvds takes place from 0 to 1. There's no "standard answer" for every process, and we'll have to find out for ourselves." in the eyes of liang ping, behind this is the constant error of a group of people。
Entering the southern pharmaceutical research and development building, technicians shuttled between the buildings. “the experiment must have been more successful than the experiment, and it is rare that the company can get us wrong.” the team of division techs knows better than anyone that it is trying to break tradition almost every day — team member liu zhioxin always leaves the lab until morning to track the results of impurity on a continuous basis, eventually increasing the purity of the succulent succubus to 99. 9 per cent; zhang wai “do not believe in expert answers” insists on replacing hydrochloric acid with more expensive sulphate, which is cost-neutral because of corrosive problems
Currently, the company has been able to produce more than five available vexanes compounds from red bean sprouts, representing 60 per cent of the national market and over 20 per cent of the global total。
The price of “gold” has become affordable for ordinary people because of technological breakthroughs. “1 kg of viol has been reduced to more than $100,000, and the viol formulations have been included in health coverage, ranging from more than 8,000 to more than 300”. Looking to the future, li yong and the team are putting together more diverse product lines。
Development of the biomedicine industry
"doing business is more like planting a tree." this is the realization of lee yong-shang ming creek for more than a decade: “natural red bean sprouts grow slowly and become a tree to the heavens will take hundreds of years to reach a thousand years old. We also expect southern pharmaceuticals to grow and grow over a long period beyond 100 years.”
On september 20th, a new anti-oncological drug from the south was licensed for listing in germany. “we have gradually extended from pvol to other anti-oncological and non-oncological raw materials, and have applied for registration in 50 countries. These two years are a critical period, and a batch of products have been prepared to enter the united states market.” lee's eyes are bright。
For the time being, the southern pharmaceutical industry is intensifying its project to produce a new series of anti-oncological drugs to scale up production, while attracting the shanghai hee-hwa pharmaceutical industry to build a hee-hwa pharmaceutical estate and produce high-end preparations. Together with the centre for innovation in the pharmaceutical industry, located in fozhou, a three-hour radius for the development of the southern pharmaceutical industry began to emerge。
Relying on the southern pharmaceuticals “big tree”, upstream and downstream enterprises gather at mingbrook, which is the country's largest production base for the alxane compounds. Twelve scientific and technical enterprises, such as heisford and haisi union pharmaceuticals, have targeted the fields of raw materials, medical intermediates and formed a model of a biomedicine industry that is based, produced, studied, market integrated。
Right now, i'm seizing the opportunity to build a biomedicine industry high ground, and mingbrook is an important distribution point for raw materials and intermediates. The national administration of chinese medicine supported ming creek, where san ming city, together with the provincial drug inspectorate, built a green production base for raw materials, and the industry was well developed。
Behind the path to good is the unfailing support of local governments. In january of this year, minghu county established the biomedicine industry development centre, which specializes in service enterprises, and successively introduced complementary policies such as the introduction of people in critical areas of concern。
When it comes to work and life in mingbrook, it's comforting to join the company for 13 years. “the people here are simple and simple, and i have more time to enrich myself.” more than 20 products had been processed over the years, many of which exceeded the same levels at home and abroad。
Grow and use red beanwood as a common pursuit of the mingbrook people. More than 3000 farmers have been actively involved in the construction of a red bean-wood base and have improved planting techniques over the years. At present, mingbrook has become the country's largest red beanwood plantation with an annual production value of about rmb 1 billion, boosting farmers ' annual incomes by over rmb 10 million。
The red beanwood industry has flourished, and the afterlife is at risk. For the time being, he had opened a new round of technical attacks on research topics such as the cultivation of sorghum trees and the development of basin views. (reporter seo wenjin, correspondent rai yuping)
